Search results for "genetics [Bladder Exstrophy]"
showing 10 items of 3025 documents
The Role of Recent Admixture in Forming the Contemporary West Eurasian Genomic Landscape
2015
Summary Over the past few years, studies of DNA isolated from human fossils and archaeological remains have generated considerable novel insight into the history of our species. Several landmark papers have described the genomes of ancient humans across West Eurasia, demonstrating the presence of large-scale, dynamic population movements over the last 10,000 years, such that ancestry across present-day populations is likely to be a mixture of several ancient groups [1, 2, 3, 4, 5, 6, 7]. While these efforts are bringing the details of West Eurasian prehistory into increasing focus, studies aimed at understanding the processes behind the generation of the current West Eurasian genetic landsc…
New records of Asteraceae for the non-native flora of Tunisia and north Africa with some nomenclatural remarks
2022
International audience; Sixteen new Asteraceae are added to the non-indigenous flora of Tunisia. Six of them (Dimorphotheca ecklonis, Gaillardia pulchella, Gazania linearis var. linearis, Guizotia abyssinica, Rudbeckia triloba and Tithonia diversifolia) are also new for the flora of North Africa. Chrysanthemum morifolium is here first reported for the Mediterranean Basin. Seven genera (Argyranthemum, Bidens, Dimorphotheca, Gaillardia, Guizotia, Rudbeckia and Tithonia) are recorded for the first time for the vascular flora of Tunisia. Most of these species escaped from gardens and pots and became casual along roadsides and/or disturbed areas after cypsela dispersion (except for Chrysanthemum…
A Brief Review of Ground Penetrating Radar Investigation Results of Ice Caps on Galindez, Winter and Skua Islands (Wilhelm Archipelago, Antarctica) f…
2019
This paper represents results of GPR surveying of the ice caps on Galindez (–64.24716W; –65.24992S), Winter (–64.25954W; –65.24944S) and Skua (–64.26530W; –65.25309S) islands (Wilhelm Archipelago, Antarctica) for the period April 2017 — January 2019. The main objectives were identification of the ice layering, monitoring of interglacial heterogeneities (crevasses, interglacial channels and voids) and measurements of the ice thickness. Methods: Surveying on the glaciers has been done with ground coupled shielded bowtie antenna VIY3-300 (300 MHz) GPR and with air coupled dipole Zond 12-e (75 MHz) antenna system. Monitoring investigation of glacier’s interior has been done with VIY3-300. Zond …
The electron affinity of astatine
2020
One of the most important properties influencing the chemical behavior of an element is the electron affinity (EA). Among the remaining elements with unknown EA is astatine, where one of its isotopes, 211At, is remarkably well suited for targeted radionuclide therapy of cancer. With the At− anion being involved in many aspects of current astatine labeling protocols, the knowledge of the electron affinity of this element is of prime importance. Here we report the measured value of the EA of astatine to be 2.41578(7) eV. This result is compared to state-of-the-art relativistic quantum mechanical calculations that incorporate both the Breit and the quantum electrodynamics (QED) corrections and…
The non-neuronal cholinergic system in peripheral blood cells: Effects of nicotinic and muscarinic receptor antagonists on phagocytosis, respiratory …
2007
Peripheral blood cells express the complete non-neuronal cholinergic system. For example synthesis of acetylcholine and nicotinic as well muscarinic receptors have been demonstrated in leucocytes isolated from human peripheral blood. In the present experiments mononuclear cells and granulocytes were isolated from the peripheral blood to investigate content and synthesis of acetylcholine as well as phenotypic functions like respiratory burst, phagocytosis and migration. Mononuclear cells (T-cells and monocytes) contained 0.36 pmol/10(6) cells acetylcholine, whereas acetylcholine content in granulocytes was 100-fold lower. Acetylcholine synthesis amounted to 23.2+/-4.7 nmol/mg protein/h and 2…
Promises of formal and informal musical activities in advancing neurocognitive development throughout childhood
2015
Adult musicians show superior neural sound discrimination when compared to nonmusicians. However, it is unclear whether these group differences reflect the effects of experience or preexisting neural enhancement in individuals who seek out musical training. Tracking how brain function matures over time in musically trained and nontrained children can shed light on this issue. Here, we review our recent longitudinal event-related potential (ERP) studies that examine how formal musical training and less formal musical activities influence the maturation of brain responses related to sound discrimination and auditory attention. These studies found that musically trained school-aged children an…
Electrophysiological Correlates of Aesthetic Music Processing
2009
We analyzed the processes of making aesthetic judgments of music, focusing on the differences between music experts and laypersons. Sixteen students of musicology and 16 control subjects (also students) judged the aesthetic value as well as the harmonic correctness of chord sequences. Event-related potential (ERP) data indicate differences between experts and laypersons in making aesthetic judgments at three different processing stages. Additionally, effects of expertise on ERP components that have previously been proven to be sensitive to musical training were replicated. The study thus provides insights into the effects of musical expertise on neural correlates of aesthetic music processi…
Untersuchungen zur Sterinsynthese des Ascomyceten Aureobasidium (Dematium) pullulans / Studies of the Sterolsynthesis in the Fungus Aureobasidium (De…
1985
Abstract Isolation and identification of sterols from culture extracts of the fungus Aureobasidium (Dematium) pullulans yielded metabolites with key function in sterol synthesis. By proof of squalene, lanosterol/dihydrolanosterol, desmosterol, ergosterol, cholesterol, stigmasterol and β-sitosterol it was possible to work out a general synthesis-scheme for the building-up of sundry sterols in Ascomycetes.
FRI0344 IL-9 and CD4+Il9+ T Lymphocytes Are over Expressed in the Synovium of Patients with Rheumatoid Arthritis, Elicited in Vitro by Citrullinated …
2014
Background Rheumatoid Arthritis (RA) is a chronic autoimmune disease characterized by joint erosion and damage. Several cytokines and recruitment of auto-reactive lymphocytes (characterized by a marked shift toward the Th1 and Th17 phenotype) to inflamed tissue is a defined feature of the disease. In addition to Th1/Th17 and Th2 cells, another subset of effector T cells, identified by the potent production of IL-9 and named Th9 cells, has been recently demonstrated. IL-9 was found in particular to be increased before the clinical onset of the articular disease in RA patients, and associated with the presence of RA-related autoantibodies and circulating biomarkers of inflammation. The exact …
TGF-β signalling is required for CD4⁺ T cell homeostasis but dispensable for regulatory T cell function.
2013
Signalling by the cytokine TGF-β regulates mature CD4+ T cell populations but is not involved in the survival and function of regulatory T cells.